Purple Smog: The Science
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HOW WE COLLECT YOUR DNA
When you order a test, we send you a sample collection kit, which consists of a swab, a tube, and a return envelope.
After washing your hands and rinsing your mouth, remove the swab from the package and brush the inside of both cheeks with it. Use enough force to brush away some of the lining of the cheek, but not so hard as to cause pain or bleeding.
After swabbing, open the tube and insert the swab end into the tube. The tube contains liquid which will preserve the sample until it arrives to us. If some spills, dont worry, it is non toxic. Once the swab is in the tube, break the tip off into the tube. The swab handle is scored to make breaking it off easy.
Close the tube up securely with the top, and mail back to us in the enclosed mailer.
Once we receive your sample, the DNA is extracted from the swabbed sample, and purified for testing. After testing is complete samples are destroyed and discarded.
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HOW WE TEST YOUR DNA
Your purified DNA is tested in the lab for 46 specific genetic mutations used in our test. No other information is tested for or determined. We aim to use lab methods that are the most quick and cost effective available, allowing us to make this test affordable to anyone who wants to know more about their genetic predispositions to cannabis consumption.
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HOW WE INTERPRET YOUR DNA RESULTS
Once we have raw data on the mutations tested for, we input this information into our software to determine the predicted outcomes based on your genetics.
Our reporting software is based on peer reviewed scientific literature that has researched the association of the tested genetic mutations with predicted response to cannabis consumption.
A personalized report is then generated that is easy to read that will help you to understand what you might expect when consuming cannabis and help you to select strains that are best for you.
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BASIC GENETICS
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Genes - A gene is a piece of your DNA responsible for coding the proteins that are created by your cells. You have typically of two copies of each gene - one from each parent. Their names are acronyms for their proteins or functions.
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DNA - Your genome is made of your DNA, which is an abbreviation for deoxyribonucleic acid. The sequence and letters of your DNA has an important role in determining everything about you. DNA has 4 possible letters, called nucleotides, throughout its entire length. These are adenine (A), cytosine (C), guanine (G), and thymine (T).
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SNP - This is an abbreviation for Single Nucleotide Polymorphism. It is defined as change in your DNA compared to the general population. The SNPs you have can play a role in your individual response to many things, including nutrition which will be explored in this report.
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Wild type - The most common type of nucleotide found in the general population. This means there is no SNP at the position in your DNA.
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Heterozygous - Among your two copies of DNA from each of your parents, one parent has a variation compared to the other at the position you are looking at. Therefore you have one copy of the SNP in your own DNA. Example: AA, CC, GG, TT.
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Homozygous - You have inherited two copies of a SNP from your parents. Example: AG, CG, TG, CT, etc.
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